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Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
Target-specific, mechanism-oriented in vitro assays post a promising alternative to traditional animal toxicology studies. Here we report the first comprehensive analysis of the Tox21 effort, a large-scale in vitro toxicity screening of chemicals. We test ∼10,000 chemicals in triplicates at 15 conce...
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| Izdano u: | Nat Commun |
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| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777217/ https://ncbi.nlm.nih.gov/pubmed/26811972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10425 |
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