Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential

Background: Mitochondrial dysfunction has been implicated in the pathogenesis of a variety of disorders including cancer, diabetes, and neurodegenerative and cardiovascular diseases. Understanding whether different environmental chemicals and druglike molecules impact mitochondrial function represen...

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Detalles Bibliográficos
Publicado en:Environ Health Perspect
Autores principales: Attene-Ramos, Matias S., Huang, Ruili, Michael, Sam, Witt, Kristine L., Richard, Ann, Tice, Raymond R., Simeonov, Anton, Austin, Christopher P., Xia, Menghang
Formato: Artigo
Lenguaje:Inglês
Publicado: NLM-Export 2014
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286281/
https://ncbi.nlm.nih.gov/pubmed/25302578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408642
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