Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential

Background: Mitochondrial dysfunction has been implicated in the pathogenesis of a variety of disorders including cancer, diabetes, and neurodegenerative and cardiovascular diseases. Understanding whether different environmental chemicals and druglike molecules impact mitochondrial function represen...

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Vydáno v:Environ Health Perspect
Hlavní autoři: Attene-Ramos, Matias S., Huang, Ruili, Michael, Sam, Witt, Kristine L., Richard, Ann, Tice, Raymond R., Simeonov, Anton, Austin, Christopher P., Xia, Menghang
Médium: Artigo
Jazyk:Inglês
Vydáno: NLM-Export 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286281/
https://ncbi.nlm.nih.gov/pubmed/25302578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408642
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