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Identification and profiling of environmental chemicals that inhibit the TGFβ/SMAD signaling pathway

The transforming growth factor beta (TGFβ) superfamily of secreted signaling molecules and their cognate receptors regulate cell fate and behaviors relevant to many developmental and disease processes. Disruption of TGFβ signaling during embryonic development can, for example, affect morphogenesis a...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Wei, Zhengxi, Sakamuru, Srilatha, Zhang, Li, Zhao, Jinghua, Huang, Ruili, Kleinstreuer, Nicole C., Chen, Yanling, Shu, Yan, Knudsen, Thomas B., Xia, Menghang
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341485/
https://ncbi.nlm.nih.gov/pubmed/31652400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.9b00228
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