Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition

BACKGROUND: Inhibition of acetylcholinesterase (AChE), a biomarker of organophosphorous and carbamate exposure in environmental and occupational human health, has been commonly used to identify potential safety liabilities. So far, many environmental chemicals, including drug candidates, food additi...

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Detalhes bibliográficos
Publicado no:Environ Health Perspect
Main Authors: Li, Shuaizhang, Zhao, Jinghua, Huang, Ruili, Travers, Jameson, Klumpp-Thomas, Carleen, Yu, Wenbo, MacKerell, Alexander D., Sakamuru, Srilatha, Ooka, Masato, Xue, Fengtian, Sipes, Nisha S., Hsieh, Jui-Hua, Ryan, Kristen, Simeonov, Anton, Santillo, Michael F., Xia, Menghang
Formato: Artigo
Idioma:Inglês
Publicado em: Environmental Health Perspectives 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041433/
https://ncbi.nlm.nih.gov/pubmed/33844597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP6993
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