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RNA toxicity induced by expanded CAG repeats in Huntington's disease
Huntington's disease (HD) belongs to the group of inherited polyglutamine (PolyQ) diseases caused by an expanded CAG repeat in the coding region of the Huntingtin (HTT) gene that results in an elongated polyQ stretch. Abnormal function and aggregation of the mutant protein has been typically de...
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| Published in: | Brain Pathol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8029335/ https://ncbi.nlm.nih.gov/pubmed/27529325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12427 |
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