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Mechanisms of RNA-induced toxicity in CAG repeat disorders
Several inherited neurodegenerative disorders are caused by CAG trinucleotide repeat expansions, which can be located either in the coding region or in the untranslated region (UTR) of the respective genes. Polyglutamine diseases (polyQ diseases) are caused by an expansion of a stretch of CAG repeat...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763438/ https://ncbi.nlm.nih.gov/pubmed/23907466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.276 |
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