Regulation of mRNA Translation by MID1: A Common Mechanism of Expanded CAG Repeat RNAs

Expansion of CAG repeats, which code for the disease-causing polyglutamine protein, is a common feature in polyglutamine diseases. RNA-mediated mechanisms that contribute to neuropathology in polyglutamine diseases are important. RNA-toxicity describes a phenomenon by which the mutant CAG repeat RNA...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Griesche, Nadine, Schilling, Judith, Weber, Stephanie, Rohm, Marlena, Pesch, Verena, Matthes, Frank, Auburger, Georg, Krauss, Sybille
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054010/
https://ncbi.nlm.nih.gov/pubmed/27774050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00226
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