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CAG repeat RNA as an auxiliary toxic agent in polyglutamine disorders

Over 20 genetic loci with abnormal expansions of short tandem repeats have been associated with human hereditary neurological diseases. Of these, specific trinucleotide repeats located in non-coding and coding regions of individual genes implicated in these disorders are strongly overrepresented. Ex...

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Bibliographic Details
Main Authors: Wojciechowska, Marzena, Krzyzosiak, Wlodzimierz J
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225975/
https://ncbi.nlm.nih.gov/pubmed/21593608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.4.15397
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