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CAG repeat RNA as an auxiliary toxic agent in polyglutamine disorders

Over 20 genetic loci with abnormal expansions of short tandem repeats have been associated with human hereditary neurological diseases. Of these, specific trinucleotide repeats located in non-coding and coding regions of individual genes implicated in these disorders are strongly overrepresented. Ex...

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Bibliographische Detailangaben
Hauptverfasser: Wojciechowska, Marzena, Krzyzosiak, Wlodzimierz J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225975/
https://ncbi.nlm.nih.gov/pubmed/21593608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.4.15397
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