Loading...

RNA toxicity in polyglutamine disorders: concepts, models, and progress of research

In Huntington's disease and other polyglutamine (polyQ) disorders, mutant proteins containing a long polyQ stretch are well documented as the trigger of numerous aberrant cellular processes that primarily lead to degeneration and, ultimately, the death of neuronal cells. However, mutant transcr...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Fiszer, Agnieszka, Krzyzosiak, Wlodzimierz J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659269/
https://ncbi.nlm.nih.gov/pubmed/23512265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-013-1016-2
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!