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RNA toxicity in polyglutamine disorders: concepts, models, and progress of research

In Huntington's disease and other polyglutamine (polyQ) disorders, mutant proteins containing a long polyQ stretch are well documented as the trigger of numerous aberrant cellular processes that primarily lead to degeneration and, ultimately, the death of neuronal cells. However, mutant transcr...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Fiszer, Agnieszka, Krzyzosiak, Wlodzimierz J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer-Verlag 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659269/
https://ncbi.nlm.nih.gov/pubmed/23512265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-013-1016-2
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