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Inhibition of mutant huntingtin expression by RNA duplex targeting expanded CAG repeats
The specific silencing of the gene of interest is the major objective of RNA interference technology; therefore, unique sequences but not abundant sequence repeats are targeted by silencing reagents. Here, we describe the targeting of expanded CAG repeats that occur in transcripts derived from the m...
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| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141264/ https://ncbi.nlm.nih.gov/pubmed/21427085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr156 |
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