Loading...

Reduction of Huntington’s Disease RNA Foci by CAG Repeat-Targeting Reagents

In several human polyglutamine diseases caused by expansions of CAG repeats in the coding sequence of single genes, mutant transcripts are detained in nuclear RNA foci. In polyglutamine disorders, unlike other repeat-associated diseases, both RNA and proteins exert pathogenic effects; therefore, dec...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Urbanek, Martyna O., Fiszer, Agnieszka, Krzyzosiak, Wlodzimierz J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368221/
https://ncbi.nlm.nih.gov/pubmed/28400719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00082
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!