ロード中...
Self-duplexing CUG repeats selectively inhibit mutant huntingtin expression
Huntington’s disease (HD) is a neurodegenerative genetic disorder caused by the expansion of the CAG repeat in the translated sequence of the HTT gene. This expansion generates a mutant huntingtin protein that contains an abnormally elongated polyglutamine tract, which, together with mutant transcri...
保存先:
| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905887/ https://ncbi.nlm.nih.gov/pubmed/24038471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt825 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|