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Oligonucleotide-based strategies to combat polyglutamine diseases
Considerable advances have been recently made in understanding the molecular aspects of pathogenesis and in developing therapeutic approaches for polyglutamine (polyQ) diseases. Studies on pathogenic mechanisms have extended our knowledge of mutant protein toxicity, confirmed the toxicity of mutant...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066792/ https://ncbi.nlm.nih.gov/pubmed/24848018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku385 |
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