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Oligonucleotide-based strategies to combat polyglutamine diseases

Considerable advances have been recently made in understanding the molecular aspects of pathogenesis and in developing therapeutic approaches for polyglutamine (polyQ) diseases. Studies on pathogenic mechanisms have extended our knowledge of mutant protein toxicity, confirmed the toxicity of mutant...

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Bibliografiska uppgifter
Huvudupphovsmän: Fiszer, Agnieszka, Krzyzosiak, Wlodzimierz J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066792/
https://ncbi.nlm.nih.gov/pubmed/24848018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku385
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