An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases

BACKGROUND: RNA interference (RNAi) and antisense strategies provide experimental therapeutic agents for numerous diseases, including polyglutamine (polyQ) disorders caused by CAG repeat expansion. We compared the potential of different oligonucleotide-based strategies for silencing the genes respon...

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Bibliografske podrobnosti
Main Authors: Fiszer, Agnieszka, Olejniczak, Marta, Switonski, Pawel M, Wroblewska, Joanna P, Wisniewska-Kruk, Joanna, Mykowska, Agnieszka, Krzyzosiak, Wlodzimierz J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359213/
https://ncbi.nlm.nih.gov/pubmed/22397573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-13-6
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