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An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases
BACKGROUND: RNA interference (RNAi) and antisense strategies provide experimental therapeutic agents for numerous diseases, including polyglutamine (polyQ) disorders caused by CAG repeat expansion. We compared the potential of different oligonucleotide-based strategies for silencing the genes respon...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359213/ https://ncbi.nlm.nih.gov/pubmed/22397573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-13-6 |
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