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CAG repeat RNA as an auxiliary toxic agent in polyglutamine disorders

Over 20 genetic loci with abnormal expansions of short tandem repeats have been associated with human hereditary neurological diseases. Of these, specific trinucleotide repeats located in non-coding and coding regions of individual genes implicated in these disorders are strongly overrepresented. Ex...

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Hlavní autoři: Wojciechowska, Marzena, Krzyzosiak, Wlodzimierz J
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225975/
https://ncbi.nlm.nih.gov/pubmed/21593608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.4.15397
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