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RNA toxicity in non‐coding repeat expansion disorders

Several neurodegenerative disorders like amyotrophic lateral sclerosis (ALS) and spinocerebellar ataxia (SCA) are caused by non‐coding nucleotide repeat expansions. Different pathogenic mechanisms may underlie these non‐coding repeat expansion disorders. While gain‐of‐function mechanisms, such as to...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Swinnen, Bart, Robberecht, Wim, Van Den Bosch, Ludo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939197/
https://ncbi.nlm.nih.gov/pubmed/31721251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101112
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