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RNA toxicity in non‐coding repeat expansion disorders

Several neurodegenerative disorders like amyotrophic lateral sclerosis (ALS) and spinocerebellar ataxia (SCA) are caused by non‐coding nucleotide repeat expansions. Different pathogenic mechanisms may underlie these non‐coding repeat expansion disorders. While gain‐of‐function mechanisms, such as to...

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書目詳細資料
發表在:EMBO J
Main Authors: Swinnen, Bart, Robberecht, Wim, Van Den Bosch, Ludo
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939197/
https://ncbi.nlm.nih.gov/pubmed/31721251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101112
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