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Modelling amyotrophic lateral sclerosis: progress and possibilities

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that primarily affects the motor system and presents with progressive muscle weakness. Most patients survive for only 2-5 years after disease onset, often due to failure of the respiratory muscles. ALS is a familial disease in ∼10%...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Van Damme, Philip, Robberecht, Wim, Van Den Bosch, Ludo
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451175/
https://ncbi.nlm.nih.gov/pubmed/28468939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.029058
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