Beta-2 microglobulin is important for disease progression in a murine model for amyotrophic lateral sclerosis

Beta-2 microglobulin (β2m) is an essential component of the major histocompatibility complex (MHC) class I proteins and in the nervous system β2m is predominantly expressed in motor neurons. As β2m can promote nerve regeneration, we investigated its potential role in amyotrophic lateral sclerosis (A...

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Detalhes bibliográficos
Main Authors: Staats, Kim A., Schönefeldt, Susann, Van Rillaer, Marike, Van Hoecke, Annelies, Van Damme, Philip, Robberecht, Wim, Liston, Adrian, Van Den Bosch, Ludo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857886/
https://ncbi.nlm.nih.gov/pubmed/24368896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00249
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