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Therapeutic potential of HDAC6 in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease in adults and no effective treatments exist. Mutations in FUS are one of the genetic causes of familial ALS. We used induced pluripotent stem cells (iPSCs) derived from FUS-ALS patients to investigate the pathological...

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Bibliografiske detaljer
Udgivet i:Cell Stress
Main Authors: Guo, Wenting, Van Den Bosch, Ludo
Format: Artigo
Sprog:Inglês
Udgivet: Shared Science Publishers OG 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551843/
https://ncbi.nlm.nih.gov/pubmed/31225447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2018.01.120
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