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Therapeutic potential of HDAC6 in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease in adults and no effective treatments exist. Mutations in FUS are one of the genetic causes of familial ALS. We used induced pluripotent stem cells (iPSCs) derived from FUS-ALS patients to investigate the pathological...

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Detalhes bibliográficos
Publicado no:Cell Stress
Main Authors: Guo, Wenting, Van Den Bosch, Ludo
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551843/
https://ncbi.nlm.nih.gov/pubmed/31225447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2018.01.120
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