Association between Age and Striatal Volume Stratified by CAG Repeat Length in Prodromal Huntington Disease

Background: Longer CAG repeat length is associated with faster clinical progression in Huntington disease, although the effect of higher repeat length on brain atrophy is not well documented. Method: Striatal volumes were obtained from MRI scans of 720 individuals with prodromal Huntington disease....

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Bibliographic Details
Main Authors: Aylward, Elizabeth, Mills, James, Liu, Dawei, Nopoulos, Peggy, Ross, Christopher A., Pierson, Ronald, Paulsen, Jane S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Huntington Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092625/
https://ncbi.nlm.nih.gov/pubmed/21593963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1235
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