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Longitudinal change in regional brain volumes in prodromal Huntington disease

OBJECTIVE: As therapeutics are being developed to target the underlying neuropathology of Huntington disease (HD), interest is increasing in methodologies for conducting clinical trials in the prodromal phase. This study was designed to examine the potential utility of structural MRI measures as out...

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Detalhes bibliográficos
Main Authors: Aylward, Elizabeth H., Nopoulos, Peggy C., Ross, Christopher A., Langbehn, Douglas R., Pierson, Ronald K., Mills, James A., Johnson, Hans J., Magnotta, Vincent A., Juhl, Andrew R., Paulsen, Jane S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105627/
https://ncbi.nlm.nih.gov/pubmed/20884680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2010.208264
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