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The structure of the native cardiac thin filament at systolic Ca(2+) levels
Every heartbeat relies on cyclical interactions between myosin thick and actin thin filaments orchestrated by rising and falling Ca(2+) levels. Thin filaments are comprised of two actin strands, each harboring equally separated troponin complexes, which bind Ca(2+) to move tropomyosin cables away fr...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8020778/ https://ncbi.nlm.nih.gov/pubmed/33753506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024288118 |
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