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C0 and C1 N-terminal Ig domains of myosin binding protein C exert different effects on thin filament activation
Mutations in genes encoding myosin, the molecular motor that powers cardiac muscle contraction, and its accessory protein, cardiac myosin binding protein C (cMyBP-C), are the two most common causes of hypertrophic cardiomyopathy (HCM). Recent studies established that the N-terminal domains (NTDs) of...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4760775/ https://ncbi.nlm.nih.gov/pubmed/26831109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518891113 |
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