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Modulation of Thin Filament Activation of Myosin ATP Hydrolysis by N-Terminal Domains of Cardiac Myosin Binding Protein-C

[Image: see text] We have used enzyme kinetics to investigate the molecular mechanism by which the N-terminal domains of human and mouse cardiac MyBP-C (C0C1, C1C2, and C0C2) affect the activation of myosin ATP hydrolysis by F-actin and by native porcine thin filaments. N-Terminal domains of cMyBP-C...

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Main Authors: Belknap, Betty, Harris, Samantha P., White, Howard D.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211651/
https://ncbi.nlm.nih.gov/pubmed/25265574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500787f
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