N-terminal domains of cardiac myosin binding protein-C cooperatively activate the thin filament.

Muscle contraction relies on interaction between myosin-based thick filaments and actin-based thin filaments. Myosin binding protein-C (MyBP-C) is a key regulator of actomyosin interactions. Recent studies established that the N’-terminal domains (NTDs) of MyBP-C can either activate or inhibit thin...

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Publicado no:Structure
Main Authors: Risi, Cristina, Belknap, Betty, Forgacs-Lonart, Eva, Harris, Samantha P., Schröder, Gunnar F., White, Howard D., Galkin, Vitold E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281772/
https://ncbi.nlm.nih.gov/pubmed/30270174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.08.007
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