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N-terminal domains of cardiac myosin binding protein-C cooperatively activate the thin filament.
Muscle contraction relies on interaction between myosin-based thick filaments and actin-based thin filaments. Myosin binding protein-C (MyBP-C) is a key regulator of actomyosin interactions. Recent studies established that the N’-terminal domains (NTDs) of MyBP-C can either activate or inhibit thin...
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| Pubblicato in: | Structure |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281772/ https://ncbi.nlm.nih.gov/pubmed/30270174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.08.007 |
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