Wird geladen...

Ca(2+)-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy

Muscle contraction relies on the interaction of myosin motors with F-actin, which is regulated through a translocation of tropomyosin by the troponin complex in response to Ca(2+). The current model of muscle regulation holds that at relaxing (low-Ca(2+)) conditions tropomyosin blocks myosin binding...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Risi, Cristina, Eisner, Jamie, Belknap, Betty, Heeley, David H., White, Howard D., Schröder, Gunnar F., Galkin, Vitold E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495243/
https://ncbi.nlm.nih.gov/pubmed/28607071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700868114
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!