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Ca(2+)-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy
Muscle contraction relies on the interaction of myosin motors with F-actin, which is regulated through a translocation of tropomyosin by the troponin complex in response to Ca(2+). The current model of muscle regulation holds that at relaxing (low-Ca(2+)) conditions tropomyosin blocks myosin binding...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495243/ https://ncbi.nlm.nih.gov/pubmed/28607071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700868114 |
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