Gene Transfer in Adeno-Associated Virus Seropositive Rhesus Macaques Following Rapamycin Treatment and Subcutaneous Delivery of AAV6, but Not Retargeted AAV6 Vectors

Adeno-associated virus (AAV) vectors such as AAV6, which shows tropism for primary human CD4(+) T cells in vitro, are being explored for delivery of anti-HIV therapeutic modalities in vivo. However, pre-existing immunity and sequestration in nontarget organs can significantly hinder their performanc...

詳細記述

保存先:
書誌詳細
出版年:Hum Gene Ther
主要な著者: Stone, Daniel, Kenkel, Elizabeth J., Loprieno, Michelle A., Tanaka, Motoko, De Silva Feelixge, Harshana S., Kumar, Arjun J., Stensland, Laurence, Obenza, Willimark M., Wangari, Solomon, Ahrens, Chul Y., Murnane, Robert D., Peterson, Christopher W., Kiem, Hans-Peter, Huang, Meei-Li, Aubert, Martine, Hu, Shiu-Lok, Jerome, Keith R.
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc., publishers 2021
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020555/
https://ncbi.nlm.nih.gov/pubmed/32998579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2020.113
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