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CRISPR-cas9 Screening Identified Lethal Genes Enriched in Cell Cycle Pathway and of Prognosis Significance in Breast Cancer

BACKGROUND: Lethal genes have not been systematically analyzed in breast cancer which may have significant prognostic value. The current study aims to investigate vital genes related to cell viability by analyzing the CRISPR-cas9 screening data, which may provide novel therapeutic target for patient...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Dev Biol
Hoofdauteurs: Sun, Xi, Wang, Zheng, Chen, Xiaosong, Shen, Kunwei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017240/
https://ncbi.nlm.nih.gov/pubmed/33816496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.646774
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