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CRISPR-cas9 Screening Identified Lethal Genes Enriched in Cell Cycle Pathway and of Prognosis Significance in Breast Cancer

BACKGROUND: Lethal genes have not been systematically analyzed in breast cancer which may have significant prognostic value. The current study aims to investigate vital genes related to cell viability by analyzing the CRISPR-cas9 screening data, which may provide novel therapeutic target for patient...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Sun, Xi, Wang, Zheng, Chen, Xiaosong, Shen, Kunwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017240/
https://ncbi.nlm.nih.gov/pubmed/33816496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.646774
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