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CRISPR-cas9 Screening Identified Lethal Genes Enriched in Cell Cycle Pathway and of Prognosis Significance in Breast Cancer

BACKGROUND: Lethal genes have not been systematically analyzed in breast cancer which may have significant prognostic value. The current study aims to investigate vital genes related to cell viability by analyzing the CRISPR-cas9 screening data, which may provide novel therapeutic target for patient...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Sun, Xi, Wang, Zheng, Chen, Xiaosong, Shen, Kunwei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017240/
https://ncbi.nlm.nih.gov/pubmed/33816496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.646774
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