Sterilizing Immunity against SARS‐CoV‐2 Infection in Mice by a Single‐Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist‐Adjuvanted Recombinant Spike Protein Vaccine

The search for vaccines that protect from severe morbidity and mortality because of infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus that causes coronavirus disease 2019 (COVID‐19) is a race against the clock and the virus. Here we describe an amphiphilic imidaz...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Jangra, Sonia, De Vrieze, Jana, Choi, Angela, Rathnasinghe, Raveen, Laghlali, Gabriel, Uvyn, Annemiek, Van Herck, Simon, Nuhn, Lutz, Deswarte, Kim, Zhong, Zifu, Sanders, Niek N., Lienenklaus, Stefan, David, Sunil A., Strohmeier, Shirin, Amanat, Fatima, Krammer, Florian, Hammad, Hamida, Lambrecht, Bart N., Coughlan, Lynda, García‐Sastre, Adolfo, De Geest, Bruno G., Schotsaert, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8014308/
https://ncbi.nlm.nih.gov/pubmed/33464672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202015362
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