Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

The search for vaccines that protect from severe morbidity and mortality as a result of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19) is a race against the clock and the virus. Several vaccine candidates are cur...

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Bibliografiset tiedot
Julkaisussa:bioRxiv
Päätekijät: Jangra, Sonia, De Vrieze, Jana, Choi, Angela, Rathnasinghe, Raveen, Laghlali, Gabriel, Uvyn, Annemiek, Van Herck, Simon, Nuhn, Lutz, Deswarte, Kim, Zhong, Zifu, Sanders, Niek, Lienenklaus, Stefan, David, Sunil, Strohmeier, Shirin, Amanat, Fatima, Krammer, Florian, Hammad, Hamida, Lambrecht, Bart N., Coughlan, Lynda, García-Sastre, Adolfo, De Geest, Bruno G., Schotsaert, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587831/
https://ncbi.nlm.nih.gov/pubmed/33106810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.10.23.344085
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