Sterilizing Immunity against SARS‐CoV‐2 Infection in Mice by a Single‐Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist‐Adjuvanted Recombinant Spike Protein Vaccine

The search for vaccines that protect from severe morbidity and mortality because of infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus that causes coronavirus disease 2019 (COVID‐19) is a race against the clock and the virus. Here we describe an amphiphilic imidaz...

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Sparad:
Bibliografiska uppgifter
I publikationen:Angew Chem Int Ed Engl
Huvudupphovsmän: Jangra, Sonia, De Vrieze, Jana, Choi, Angela, Rathnasinghe, Raveen, Laghlali, Gabriel, Uvyn, Annemiek, Van Herck, Simon, Nuhn, Lutz, Deswarte, Kim, Zhong, Zifu, Sanders, Niek N., Lienenklaus, Stefan, David, Sunil A., Strohmeier, Shirin, Amanat, Fatima, Krammer, Florian, Hammad, Hamida, Lambrecht, Bart N., Coughlan, Lynda, García‐Sastre, Adolfo, De Geest, Bruno G., Schotsaert, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8014308/
https://ncbi.nlm.nih.gov/pubmed/33464672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202015362
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