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Cigarette Smoke Activates NOTCH3 to Promote Goblet Cell Differentiation in Human Airway Epithelial Cells

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States and is primarily caused by cigarette smoking. Increased numbers of mucus-producing secretory (“goblet”) cells, defined as goblet cell metaplasia or hyperplasia (GCMH), contributes significantly to C...

詳細記述

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書誌詳細
出版年:Am J Respir Cell Mol Biol
主要な著者: Bodas, Manish, Moore, Andrew R., Subramaniyan, Bharathiraja, Georgescu, Constantin, Wren, Jonathan D., Freeman, Willard M., Brown, Brent R., Metcalf, Jordan P., Walters, Matthew S.
フォーマット: Artigo
言語:Inglês
出版事項: American Thoracic Society 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008804/
https://ncbi.nlm.nih.gov/pubmed/33444514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2020-0302OC
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