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Prenatal Secondhand Cigarette Smoke Promotes Th2 polarization and impairs goblet cell differentiation and airway mucus formation

Parental, particularly maternal, smoking increases the risk of childhood allergic asthma and infection. Similarly, in a murine allergic asthma model, prenatal plus early postnatal exposure to secondhand cigarette smoke (SS) exacerbates airway hyperreactivity and Th2 responses in the lung. However, t...

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Detalhes bibliográficos
Main Authors: Singh, Shashi P., Gundavarapu, Sravanthi, Peña-Philippides, Juan C., Rir-sima-ah, Jules, Mishra, Neerad C., Wilder, Julie A., Langley, Raymond J., Smith, Kevin R., Sopori, Mohan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197944/
https://ncbi.nlm.nih.gov/pubmed/21930963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101567
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