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Nicotine Inhibits FcεRI-induced Cysteinyl Leukotrienes and Cytokine Production without Affecting Mast Cell Degranulation Through Alpha7/Alpha9/Alpha10-nicotinic Receptors

Smokers are less likely to develop some inflammatory and allergic diseases. In Brown-Norway rats, nicotine inhibits several parameters of allergic asthma including the production of Th2 cytokines and the cysteinyl leukotriene LTC(4). Cysteinyl leukotrienes are primarily produced by mast cells, and t...

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Detalhes bibliográficos
Main Authors: Mishra, Neerad C., Rir-sima-ah, Jules, Boyd, R. Thomas, Singh, Shashi P., Gundavarapu, Sravanthi, Langley, Raymond J., Razani-Boroujerdi, Seddigheh, Sopori, Mohan L
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954495/
https://ncbi.nlm.nih.gov/pubmed/20505147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902227
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