SPDEF regulates goblet cell hyperplasia in the airway epithelium

Goblet cell hyperplasia and mucous hypersecretion contribute to the pathogenesis of chronic pulmonary diseases including cystic fibrosis, asthma, and chronic obstructive pulmonary disease. In the present work, mouse SAM pointed domain-containing ETS transcription factor (SPDEF) mRNA and protein were...

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Main Authors: Park, Kwon-Sik, Korfhagen, Thomas R., Bruno, Michael D., Kitzmiller, Joseph A., Wan, Huajing, Wert, Susan E., Khurana Hershey, Gurjit K., Chen, Gang, Whitsett, Jeffrey A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810569/
https://ncbi.nlm.nih.gov/pubmed/17347682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29176
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