SPDEF regulates goblet cell hyperplasia in the airway epithelium

Goblet cell hyperplasia and mucous hypersecretion contribute to the pathogenesis of chronic pulmonary diseases including cystic fibrosis, asthma, and chronic obstructive pulmonary disease. In the present work, mouse SAM pointed domain-containing ETS transcription factor (SPDEF) mRNA and protein were...

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Главные авторы: Park, Kwon-Sik, Korfhagen, Thomas R., Bruno, Michael D., Kitzmiller, Joseph A., Wan, Huajing, Wert, Susan E., Khurana Hershey, Gurjit K., Chen, Gang, Whitsett, Jeffrey A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2007
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810569/
https://ncbi.nlm.nih.gov/pubmed/17347682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29176
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