Spdef Null Mice Lack Conjunctival Goblet Cells and Provide a Model of Dry Eye

Goblet cell numbers decrease within the conjunctival epithelium in drying and cicatrizing ocular surface diseases. Factors regulating goblet cell differentiation in conjunctival epithelium are unknown. Recent data indicate that the transcription factor SAM-pointed domain epithelial-specific transcri...

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Bibliografiske detaljer
Main Authors: Marko, Christina K., Menon, Balaraj B., Chen, Gang, Whitsett, Jeffrey A., Clevers, Hans, Gipson, Ilene K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2013
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702735/
https://ncbi.nlm.nih.gov/pubmed/23665202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.03.017
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