Spdef Null Mice Lack Conjunctival Goblet Cells and Provide a Model of Dry Eye

Goblet cell numbers decrease within the conjunctival epithelium in drying and cicatrizing ocular surface diseases. Factors regulating goblet cell differentiation in conjunctival epithelium are unknown. Recent data indicate that the transcription factor SAM-pointed domain epithelial-specific transcri...

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Detalhes bibliográficos
Main Authors: Marko, Christina K., Menon, Balaraj B., Chen, Gang, Whitsett, Jeffrey A., Clevers, Hans, Gipson, Ilene K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702735/
https://ncbi.nlm.nih.gov/pubmed/23665202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.03.017
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