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Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation

Epithelial cells that line the conducting airways provide the initial barrier and innate immune responses to the abundant particles, microbes, and allergens that are inhaled throughout life. The transcription factors SPDEF and FOXA3 are both selectively expressed in epithelial cells lining the condu...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Rajavelu, Priya, Chen, Gang, Xu, Yan, Kitzmiller, Joseph A., Korfhagen, Thomas R., Whitsett, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463206/
https://ncbi.nlm.nih.gov/pubmed/25866971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79422
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