Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure

Adenosine A(1) receptors (A(1)R) are a potential target for cardiac injury treatment due to their cardioprotective/antihypertrophic actions, but drug development has been hampered by on-target side effects such as bradycardia and altered renal hemodynamics. Biased agonism has emerged as an attractiv...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Pharmacol
Main Authors: Rueda, Patricia, Merlin, Jon, Chimenti, Stefano, Feletou, Michel, Paysant, Jerome, White, Paul J., Christopoulos, Arthur, Sexton, Patrick M., Summers, Roger J., Charman, William N., May, Lauren T., Langmead, Christopher J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021
נושאים:
Pharmacology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7991592/
https://ncbi.nlm.nih.gov/pubmed/33776771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.628060
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים