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New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism

Adenosine receptors are a family of GPCRs containing four subtypes (A(1), A(2A), A(2B) and A(3) receptors), all of which bind the ubiquitous nucleoside adenosine. These receptors play an important role in physiology and pathophysiology and therefore represent attractive drug targets for a range of c...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Vecchio, Elizabeth A, Baltos, Jo‐Anne, Nguyen, Anh T N, Christopoulos, Arthur, White, Paul J, May, Lauren T
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177620/
https://ncbi.nlm.nih.gov/pubmed/29679502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14337
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