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New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism

Adenosine receptors are a family of GPCRs containing four subtypes (A(1), A(2A), A(2B) and A(3) receptors), all of which bind the ubiquitous nucleoside adenosine. These receptors play an important role in physiology and pathophysiology and therefore represent attractive drug targets for a range of c...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Vecchio, Elizabeth A, Baltos, Jo‐Anne, Nguyen, Anh T N, Christopoulos, Arthur, White, Paul J, May, Lauren T
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177620/
https://ncbi.nlm.nih.gov/pubmed/29679502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14337
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