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Only One Protomer Is Active in the Dimer of SARS 3C-like Proteinase
The severe acute respiratory syndrome coronavirus 3C-like protease has been proposed to be a key target for structurally based drug design against SARS. The enzyme exists as a mixture of dimer and monomer, and only the dimer was considered to be active. In this report, we have investigated, using mo...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7990651/ https://ncbi.nlm.nih.gov/pubmed/16565086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M510745200 |
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