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The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase()

The 3C-like proteinase of severe acute respiratory syndrome (SARS) coronavirus has been proposed to be a key target for structural-based drug design against SARS. Accurate determination of the dimer dissociation constant and the role of the N-finger (residues 1–7) will provide more insights into the...

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Dades bibliogràfiques
Publicat a:Biochem Biophys Res Commun
Autors principals: Wei, Ping, Fan, Keqiang, Chen, Hao, Ma, Liang, Huang, Changkang, Tan, Lei, Xi, Dong, Li, Chunmei, Liu, Ying, Cao, Aoneng, Lai, Luhua
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Inc. 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092940/
https://ncbi.nlm.nih.gov/pubmed/16329994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2005.11.102
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